99mTc-DTPA and 131I-hippuran findings in liver transplant recipients treated with cyclosporin A.

Liver-function studies in heart-transplant recipients treated with cyclosporin A.

Cyclosporine (CsA) hepatotoxicity has been reported but has not been studied systematically. This study includes 17 patients undergoing heart transplantation (HTx) and being treated with CsA, azathioprine, and corticosteroids. We assessed liver function in these patients before HTx and during the following month by five biological tests: total bile acids (BA), alkaline phosphatase (AP), gamma-g...

Acute bone-marrow oedema in cyclosporin-treated renal transplant recipients.

Transient musculoskeletal pain may occur in renal transplant patients on cyclosporin (CyA). Of 28 consecutive patients transplanted in this unit between 20 January 1995 and 2 May 1996, eight (two published elsewhere) developed this problem. Before transplantation, three of the patients had received prednisone intermittently or continuously for 15, 5 and 2 years, for asthma, crescentic GN and SL...

cyclosporin A in renal transplant recipients

Thirteen non-diabetic renal transplant recipients had various aspects of carbohydrate and ipid metabolism studied before and after conversion from cyclosporin A to azathioprine. No patient had a glucose tolerance test result diagnostic ofdiabetes meflitus before conversion, and there was no change in fasting glucose or immunoreactive insulin values after conversion. There was, however, a fail i...

Convulsions associated with cyclosporin A in renal transplant recipients.

Cyclosporin A has proved to be a valuable drug both in the prevention of graft rejection after solid organ transplantation' and in the prevention of graft versus host disease after bone marrow transplantation.2 Caine et al treated the first cadaver renal allograft recipients with cyclosporin A in 1978,3 and toxicity due to the drug was noted soon afterwards. The adverse effects in transplant re...

dyslipidemia in renal transplant recipients treated with cyclosporine a